Commentary: Are birthweight and cardiovascular associations due to fetal programming?
نویسندگان
چکیده
منابع مشابه
Fetal Programming Programming of Hypertension Associations of Plasma Aldosterone in Adult Men and Women With Birthweight, Cortisol, and Blood Pressure
Animal models suggest that explanations for the association of low birthweight with adult hypertension may include chronic activation of the hypothalamic-pituitary-adrenal or renin-angiotensin-aldosterone axes. In humans, low birthweight predicts elevated plasma cortisol, but associations with aldosterone have not been reported. We measured aldosterone in serum samples from 205 men and 106 wome...
متن کاملFetal programming of cardiovascular function through exposure to maternal undernutrition.
A substantial and robust body of epidemiological evidence indicates that prenatal dietary experience may be a factor determining cardiovascular disease risk. Retrospective cohort studies indicate that low birth weight and disproportion at birth are powerful predictors of later disease risk. This prenatal influence on non-communicable disease in later life has been termed programming. Maternal n...
متن کاملHuman embryonic growth trajectories and associations with fetal growth and birthweight.
STUDY QUESTION How do human embryonic growth trajectories evolve in the first trimester, and is first-trimester embryonic growth associated with fetal growth and birthweight (BW)? SUMMARY ANSWER Human embryonic growth rates increase between 9 and 10 weeks of gestation and are associated with mid-pregnancy fetal growth and BW. WHAT IS KNOWN ALREADY Fetal growth is associated with health and ...
متن کاملSri Lankan fetal/ birthweight charts: validation of global reference for fetal weight and birthweight percentiles.
INTRODUCTION Small for gestational age (SGA) is defined as birthweight below the tenth centile at a particular gestational week. Birthweight centiles for different populations are varied. Generic reference for fetal weight and birthweight that could be adapted to local populations was recently described. The purpose of this study was to validate the reference for birthweights adapted to the loc...
متن کاملRenal, cardiovascular and metabolic effects of fetal programming.
Disturbed fetal development has long-lasting effects on the offspring, specifically a higher risk of renal, cardiovascular and metabolic disease in adult life as postulated by Barker’s hypothesis. Relevant to renal outcomes of the offspring are maternal factors such as pre-eclampsia, malnutrition, smoking, drugs etc. The main renal abnormalities in the offspring include reduced nephron number a...
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ژورنال
عنوان ژورنال: International Journal of Epidemiology
سال: 2001
ISSN: 1464-3685,0300-5771
DOI: 10.1093/ije/30.4.862